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KMID : 0665220160290030411
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Korean Journal of Food and Nutrition
2016 Volume.29 No. 3 p.411 ~ p.419
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Effect of Mulberry Extract on the Lipid Profile and Liver Function in Mice Fed a High Fat Diet
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Choi Kyung-soon
Kim Yong-Hwan
Shin Kyung-Ok
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Abstract
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In this study, we determined the effect of the mulberry leaf powder on blood lipid metabolism and liver function improvement of mice fed a high fat diet. The mulberry leaf showed a moisture content of 10.74±0.56%, ash 9.67±0.56%, crude protein 25.24±1.02%, and crude fat 2.66±0.08%. In the group with high fat diet supplemented with mulberry leaf powder, serum low-density lipoprotein (LDL-cholesterol) and total cholesterol levels were significantly lower (p<0.05); also, serum phospholipid and aspartate amino transferase (AST) levels were significantly lower (p<0.05). Serum insulin and leptin levels were high in mice fed a high fat diet; however, addition of mulberry leaf powder 10% in the diet had no significant effect on blood insulin and leptin control. The results of the study suggested that various plant sterols in mulberry leaf improve lipid metabolism and liver function in ICR-mice.
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KEYWORD
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mulberry leaf , general components , LDL-cholesterol , total cholesterol , aspartate aminotransferase
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